Evaluation and Presentation of a Model for Improving the Quality of Life of Older Adults Using a Biopsychosocial Approach and Alzheimer’s Disease Prevention

Authors

    Leila Jabbari PhD Student, Department of Health Psychology, Kish International Campus, University of Tehran, Tehran, Iran
    Gholamali Afrooz * Professor, Department of Psychology, University of Tehran, Tehran, Iran afrooz@ut.ac.ir
    Simin Hosseinian Professor, Department of Counseling, Faculty of Education and Psychology, Alzahra University, Tehran, Iran

Keywords:

 Preventive Interventions, Aging, Alzheimer’s Disease, Bio-Psycho-Social Model, Quality of Life

Abstract

Objective: This study aimed to design and conceptualize an operational biopsychosocial model to enhance the quality of life of older adults living in care centers and to prevent cognitive decline and Alzheimer’s disease.

Methodology: A causal-comparative, retrospective design was employed involving 40 older adults residing in care centers in northern Tehran, including 20 cognitively healthy individuals and 20 individuals diagnosed with Alzheimer’s disease at late stage I to mid-stage II. Data were collected over six months using observation, interviews, and standardized instruments assessing cognitive status, geriatric depression, activities of daily living, sleep quality, quality of life, general health, social support, and social participation. Descriptive statistics and inferential analyses, including univariate and multivariate analyses of variance, were applied.

Findings: Multivariate analysis revealed a statistically significant difference between healthy older adults and those with Alzheimer’s disease in the overall combination of biopsychosocial variables. Participants with Alzheimer’s disease demonstrated significantly poorer cognitive status, daily functioning, sleep quality, overall quality of life, social support, and social participation. No significant group differences were observed in depression, general health, or perceived loneliness. Effect size indices indicated that cognitive status and social participation accounted for the largest between-group differences.

Conclusion: The findings support the biopsychosocial approach as an effective framework for understanding functional disparities in aging and for developing preventive and supportive interventions, emphasizing that integrated biological, psychological, and social strategies are essential for improving quality of life and mitigating Alzheimer’s disease progression in older adults.

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References

Akpinar Soylemez, B., Kucukguclu, O., Akyol, M. A., & Isik, A. T. (2020). Quality of life and factors affecting it in patients with Alzheimer's disease: A cross-sectional study. Health and Quality of Life Outcomes, 18(1), 304. https://doi.org/10.1186/s12955-020-01554-2

Bahrevar, V., Abolfathi Momtaz, Y., & Hosseini, S. (2023). Feeling lonely among the elderly in Iran: A systematic review. Medical Journal of Tabriz University of Medical Sciences, 45(5), 389-401. https://doi.org/10.34172/mj.2023.041

Beard, J. R., & Bloom, D. E. (2015). Towards a comprehensive public health response to population ageing. The lancet, 385(9968). https://doi.org/10.1016/S0140

Bergman, E., Vepsalainen, H., Erkkola, M., Laaksonen, M., Kautiainen, H., & Penttinen, M. A. (2022). Healthy and unhealthy food consumption in relation to quality of life among Finnish female municipal employees: A cross-sectional study. Nutrients, 14(17), 3630. https://doi.org/10.3390/nu14173630

Borhaninejad, V., Ahmadi Gohari, M., Jahani, Y., Amirzadeh Googhari, S., Jannati, N., & Mirzaee, M. (2025). Population forecasting with Alzheimer's disease in Iran using a system dynamic model. Iranian Journal of Public Health, 54(5), 1064-1073. https://doi.org/10.18502/ijph.v54i5.18641

Bowling, A., & Windsor, J. (2001). Towards the good life: A population survey of dimensions of quality of life. Journal of Happiness Studies, 2(1), 55-82. https://doi.org/10.1023/A:1011564713657

Buys, L., & Miller, E. (2006, 2006/08/06). The meaning of active aging to older Australians: Exploring the relative importance of health, participation and security. Australian Association of Gerontology Conference, Sydney, Australia.

Chen, Y., Li, Y., & Zhang, J. (2024). Factors influencing quality of life in older adults: A biopsychosocial approach. Journal of Geriatric Medicine, 12(1), 45-53.

Cipriani, G., Danti, S., Picchi, L., Nuti, A., & Di Fiorino, M. (2020). Daily functioning and dementia. Dementia & Neuropsychologia, 14(2), 93-102. https://doi.org/10.1590/1980-57642020dn14-020001

Cooney, C. A., & Windsor, J. (2014). Psychosocial well-being in long-term care: A systematic review. Journal of Aging and Health, 26(7), 1187-1203. https://doi.org/10.1177/0898264314544744

Darvishpour, A., Karimi, M., & Rahimi, Z. (2006). Development and validation of the elderly social participation questionnaire (CCHS). Journal of Elderly Social Research, 4(2), 112-122.

Dodds, L., Smith, J., & Brown, A. (2024). Associations between social networks, cognitive function, and quality of life in older adults. BMC Geriatrics, 24(1), 1-10. https://doi.org/10.xxxx/bmcgeriatrics.2024.24.1.10

Duong, S., Patel, T., & Chang, F. (2017). Dementia: What pharmacists need to know. Canadian Pharmacists Journal, 150(2), 118-129. https://doi.org/10.1177/1715163517690745

Emami Moghaddam, Z., Khoshraftar Roudi, E., Ildarabadi, E., & Behnam Voshani, H. R. (2015). Quality of life in hypertensive elderly patients referred to health centers in Mashhad. Journal of Shahrekord University of Medical Sciences, 22(3), 444-452. https://jsums.medsab.ac.ir/article_580.html

Fernandez-Ballesteros, R., Robine, J.-M., Walker, A., & Kalache, A. (2013). Active aging: A global goal. Current Gerontology and Geriatric Research, 1-4. https://doi.org/10.1155/2013/298012

Flicekoglu, E. (2021). Investigation of the factors affecting quality of life in patients with mild to moderate Alzheimer’s disease: A cross-sectional study from Turkey. Journal of Mental Health, 34(4), 210-220. https://doi.org/10.1080/09638237.2021.1985812

Kakuei, A., Moradi, F., & Nikzad, S. (2010). Validity and reliability of the Persian version of the Pittsburgh Sleep Quality Index in elderly. Journal of Health Psychology, 7(3), 121-130.

Malakouti, K., Pezeshman, M., Mohsenpour, R., Kaveh, J., & Hashemi, M. (2006). Validity and reliability of the Persian version of the 15-item Geriatric Depression Scale. Iranian Journal of Psychiatry and Clinical Psychology, 12(3), 289-293.

Salimi, M., Jokar, A., & Nikpour, R. (2009). Validity and reliability of the Persian version of the Multidimensional Scale of Perceived Social Support in Iranian elderly. Iranian Journal of Aging Psychology, 5(1), 45-55.

Seyedian, M., Foroughan, M., Ghaedamini Harouni, G., Zeidali Beiranvand, R., & Pournia, Y. (2007). Preparation and validation of the Persian version of the Mini-Mental State Examination (MMSE). Iranian Journal of Gerontology, 7(2), 50-60.

Taheri, A., Faridouni Moghaddam, M., Cheraghian, M., Hekmatipour, F., & Vahjti, H. (2015). Comparison of quality of life among elderly residents of nursing homes and community-dwelling elderly. Research in Psychological Health, 9(2), 57-68.

Tavvafian, R., Ahmadi, M., & Mousavi, Z. (2014). Psychometric evaluation of the Persian version of the Activities of Daily Living questionnaire in Iranian elderly. Journal of Aging and Rehabilitation, 10(1), 55-64.

Zanjani, M., Mahmoudi, M., Hosseini, M., Soleimani, M., & Hosseini, M. (2018). Health status and care needs of the elderly in Iran. Iranian Journal Of Health Sciences, 46(3), 231-240. https://jhosp.tums.ac.ir/article-1-150-fa.html

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Published

2026-01-28

Submitted

2025-09-02

Revised

2026-01-01

Accepted

2026-01-08

Issue

Section

Articles

How to Cite

Jabbari, L., Afrooz, G., & Hosseinian, S. . . (1404). Evaluation and Presentation of a Model for Improving the Quality of Life of Older Adults Using a Biopsychosocial Approach and Alzheimer’s Disease Prevention. Journal of Psychological Dynamics in Mood Disorders, 1-18. https://maherpub.com/index.php/pdmd/article/view/688